Don't worry, these questions come up plenty.
This is the usual spot for 'minor trimming' for the front tire when going with larger tires.
Rear tires will not require any trimming for slightly larger tires. Going too big would also require serious cutting of the front splash guards (or removal as some have done) and front bumper fascia, which could get ugly.
The
green line is what I had to trim off of my front splash guards, the bottom has an angle of about 45 degrees.
The
yellow line is what I had to trim off of the front wheel well liners, both front & back sides, for the front tires.
I also did some trimming of my wheel well liners when I had 20's on my truck, due to the wider 285's. You can also see in the picture the upwards oval cutting on the wheel well liner. All my trimming was done with a Dremel, you can use anything that will cut plastic, the only material that you may need to trim. The trimming is so minor that you will never notice it with the wheels mounted.
Most of us change the garbage OEM struts up front while everything is apart, and some get new strut mounts too, but I did not.